Influence of bone cements on bone-screw interfaces in the third metacarpal and third metatarsal bones of horses.
نویسندگان
چکیده
OBJECTIVE To compare biomechanical strength, interface quality, and effects of bone healing in bone-implant interfaces that were untreated or treated with calcium phosphate cement (Ca-cement), magnesium phosphate cement (Mg-cement), or polymethylmethacrylate (PMMA) in horses. ANIMALS 6 adult horses. PROCEDURES 4 screw holes were created (day 0) in each third metacarpal and third metatarsal bone of 6 horses. In each bone, a unicortical screw was placed in each hole following application of Ca-cement, Mg-cement, PMMA, or no treatment (24 screw holes/treatment). Screws were inserted to 2.82 N m torque. Horses were euthanized and bones were harvested at day 5 (16 screw holes/treatment) or day 182 (8 screw holes/treatment). Radiography, biomechanical testing, histomorphometry, and micro-computed tomography were performed to characterize the bone-implant interfaces. RESULTS Use of Mg-cement increased the peak torque to failure at bone-implant interfaces, compared with the effects of no treatment and Ca-cement, and increased interface toughness, compared with the effects of no treatment, Ca-cement, and PMMA. Histologically, there was 44% less Ca-cement and 69% less Mg-cement at the interfaces at day 182, compared with amounts present at day 5. Within screw threads, Ca-cement increased mineral density, compared with PMMA or no treatment. In the bone adjacent to the screw, Mg-cement increased mineral density, compared with PMMA or no treatment. One untreated and 1 Ca-cement-treated screw backed out after day 5. CONCLUSIONS AND CLINICAL RELEVANCE In horses, Mg-cement promoted bone-implant bonding and adjacent bone osteogenesis, which may reduce the risk of screw loosening.
منابع مشابه
Comparison of radiographic changes of the proximal third metacarpal and metatarsal bones in horses with and without proximal suspensory desmitis
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Radiographic features of the dorsal condylar sagittal ridge of the third metacarpal and metatarsal bones in young Warmblood stallions.
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ورودعنوان ژورنال:
- American journal of veterinary research
دوره 70 8 شماره
صفحات -
تاریخ انتشار 2009